Road
The city is connected to the North-South Corridor National Highway (India) via the four-lane National Highway 544,previously NH 47. The highway traverses through the entire length and breadth of the city from different points and provides access to the nearby cities such of Kochi, Palakkad and Coimbatore. NH 544 provides two main exit points at Mannuthy and which is bypass to the Thrissur city and Thalore.

The ongoing construction of Mannuthy- Vadakkencherry 6 lane national highway is a major traffic problem in the district. A tunnel was planned to built in Kuthiran which is the main point of accidents. During 2018 floods there was a landslide in Kuthiran the roads were jammed for 5 days. Central and state governments are not willing to take any actions. As it is one the main roads which connect neighbouring states to Kerala. When Monsoon starts roads will be fully damaged, people were forced to risk their lives inorder to provide income in their family.

The city is largely dependent on private buses, taxis and auto rickshaws (called autos) for public transport. A transit terminal mobility hub situated in Puzhakkal is also under wraps to be made on lines of Vyttila Mobility Hub to reduce traffic congestion is recently approved to be realised soon.

State-owned Kerala State Road Transport Corporation (KSRTC) runs inter-state, inter-district and city services. Thrissur has three bus stations, the Shaktan Thampuran Private Bus Stand, Thrissur in Sakthan Thampuran Nagar, Vadakke Stand (Northern Bus Stand) and the Thrissur KSRTC Bus Station near the Thrissur Railway Station. State Highway (SH 69) Thrissur-Kuttippuram Road, SH 22 Kodungallur – Shornur Road, SH 75 Thrissur – Kanjani – Vadanappally Road are the three state highways which connect city with its suburbs and municipalities.

Railway
The Southern Railway Zone of the Indian Railways operates the main rail transport system in Thrissur. There are four railway stations in Thrissur city. Thrissur Railway Station, one of the four A+ railway station in Kerala provides trains to three directions and lies on the busy Shoranur-Cochin Harbour section. It has a satellite station, Punkunnam railway station and two minor stations, Ollur Railway Station and Mulankunnathukavu Railway Station. Thrissur Railway Station also connects to the temple town of Guruvayur by Thrissur-Guruvayur Section. In addition, Southern Railways is running a suburban railway system connecting Thrissur to Kochi and Palakkad using Mainline Electrical Multiple Unit services (MEMU).

Air
The city is served by Cochin International Airport (Nedumbassery), which is about 55 kilometres away. Direct domestic flights are available to major Indian cities like New Delhi, Mumbai, Hyderabad, Chennai, Bangalore, Pune, Nagpur, Kolkata, Visakhapatnam (proposed). International flights to Middle East cities like Dubai, Kuwait, Bahrain, Muscat, Sharjah, Jeddah, Riyadh, Doha and to Southeast Asian cities Bangkok, Singapore and Kuala Lumpur are available here. It has a dedicated Heli-taxi service and Chartered flights. Calicut International Airport at Karipur, is 80 kilometers from the city and Coimbatore Airport, which is 114 kilometers from the city also can be used by travellers.