Road

Guruvayur can be accessed from Kochi city by National Highway NH 66, which starts from Edapally in Kochi and interchange from Chavakkad. Guruvayur can be accessed from Thrissur city by state highway 49, which starts from Guruvayur and ends in state highway 69 at Choondal. Guruvayur can be accessed from Kozhikkode city by Chamravattom, interchange from Chavakkad. From city there are regular private and State-owned Kerala State Road Transport Corporation (KSRTC) buses. There is a private and a Kerala State Road Transport Corporation bus stand in Guruvayur which run inter-state, inter-district and city services. There are good frequency of buses from Palakkad, Calicut also.

Railway

The main rail transport system in Guruvayur is operated by the Southern Railway Zone of Indian Railways. Guruvayur Railway Station lies in the Thrissur-Guruvayur Section. It is the last station in this section. There are two passenger trains operating from Guruvayur Railway Station to Ernakulam Junction and another two passenger trains to Thrissur Railway Station every day. An overnight express train to Chennai Egmore via Ernakulam Junction, Kollam Junction, Thiruvananthapuram, Nagercoil Junction, Madurai, Trichy is also running from Guruvayur Railway Station every day. Thrissur Railway Station is the major rail head near to Guruvayur from where you can get all South Indian and North Indian trains.

Air

Cochin International Airport is the nearest airport, which is 72  km from Guruvayur. All international, domestic and chartered flights are available here. Calicut International Airport at Karipur is about 100 km away.