Christianity is the predominant religion in the Athirampuzha region, followed by Hinduism and Islam. The St. Mary's Church at Athirampuzha is one of the oldest in Kerala. The Venmanatoor Sri Krishna Swami Temple (തൃക്കേൽ) is situated in Athirampuzha. The famous Vedhagiri hill is a Hindu pilgrim center located in the ward 1 of Athirampuzha panchayath. It is believed that the pandavas (Mahābhārata) visited the vyasa during their exile life. Remnants of the monastery are seen on the top of a small hill called Vedhagirimala. Hindus often visit the place and pray for their forefathers at the temple (Sri Dharma Shastha Kshethram) and have a snanam{Sanskrit} (holy bath) at the pond near the temple. Charis Bhavan, a well-known MSFS charismatic retreat center also located in Athirampuzha. The Ettumanoor Mahadevar Temple is situated near Athirampuzha. Also, there are multiple small Hindu temples and mosques in different parts of Athirampuzha.